🔎Introduction : Smallpox is a serious and often deadly viral infection. It's contagious — meaning it spreads from person to person — and can cause permanent scarring. Sometimes, it causes disfigurement. Smallpox has affected humans for thousands of years but was wiped out worldwide by 1980 thanks to smallpox vaccines. It's no longer found naturally in the world. The last case of naturally occurring smallpox was reported in 1977. 🔎History of Smallpox : The origin of smallpox is unknown . The finding of smallpox-like rashes on Egyptian mummies suggests that smallpox has existed for at least 3,000 years. The earliest written description of a disease like smallpox appeared in China in the 4 th century CE (Common Era). A huge pandemic reached from Europe to the Middle East in 1614, and epidemics arose regularly in Europe throughout the 17th and 18th centuries. There were frequent outbreaks in the American coloni...